• Vice President Manufacturing – Biotechnology – Laguna Source – San Diego, CA

    Updated: 2010-01-31 15:00:16
    Vice President Manufacturing - Biotechnology Vice President Manufacturing - Biotechnology Vice President Manufacturing - Biotechnology Southern California... From Monster - 31 Jan 2010 15:00:16 GMT - save job, email, more...

  • Drug Discovery Scientist – Orphagen Pharmaceuticals – San Diego, CA

    Updated: 2010-01-31 07:58:12
    2 years of laboratory experience, preferably in the pharmaceutical or biotechnology industry. Proficiency with data analytical software (such as MS Excel and... From BioSpace.com - 31 Jan 2010 07:58:12 GMT - save job, email, more...

  • Picture of the Day - 31 January 2010 [The Questionable Authority]

    Updated: 2010-01-31 06:02:16
    Now on ScienceBlogs : Coal and the fossil record of climate change in the Canadian High Arctic Last 24 Hrs Life Science Physical Science Environment Humanities Education Politics Medicine Brain Behavior Technology Information Science Jobs The Questionable Authority Latest Posts Archives About RSS Contact Search Profile Mike Dunford was a graduate student in the Department of Zoology at the University of Hawaii , Manoa , where he studied evolution . Life as an army spouse has since moved him on to Pensacola , where he's currently trying to figure out what to do next . While he's doing that , he writes stuff here , although not usually in the third person . He's also a contributer to The Pandas Thumb As is the case with everyone else here , his opinions are his own , and do not necessarily represent those of any organization he is affiliated with . follow questauthority at http : twitter.com Recent Posts Picture of the Day 31 January 2010 Picture of the Day 30 January 2010 Picture of the Day 29 January 2010 Picture of the Day 28 January 2010 Picture of the Day 27 January 2010 Picture of the Day 26 January 2010 Picture of the Day 25 January 2010 Picture of the Day 24 January 2010

  • Craig Venter talks about creating synthetic life

    Updated: 2010-01-31 06:00:21
    (Source: Biosingularity)

  • What you eat after exercise matters

    Updated: 2010-01-30 22:21:24
    Many of the health benefits of aerobic exercise are due to the most recent exercise session (rather than weeks, months and even years of exercise training), and the nature of these benefits can be greatly affected by the food we eat afterwards, according to a study published in the Journal of Applied Physiology (http://jap.physiology.org). “Differences in [...] (Source: Biosingularity)

  • Secrets of immunologic memory

    Updated: 2010-01-30 22:19:17
    Investigators at Sanford-Burnham Medical Research Institute (Sanford-Burnham) have discovered a new way the cell surface protein, CD44, helps specific T helper (Th1) cells develop immunologic memory. Linda Bradley, Ph.D., Bas Baaten, Ph.D., and colleagues determined that without CD44, Th1 cells died off during their initial immune response and were unable to generate immunologic memory. This [...] (Source: Biosingularity)

  • Young Blood Reverses Signs of Aging in Old Mice

    Updated: 2010-01-30 22:17:28
    The antiaging power of blood might not be just the stuff of vampire stories. According to new research from Harvard University, an unspecified factor in the blood of young mice can reverse signs of aging in the circulatory system of older ones. It’s not yet clear how these changes affect the animals’ overall health or [...] (Source: Biosingularity)

  • Evolution of Adaptive Behaviour in Robots by Means of Darwinian Selection

    Updated: 2010-01-30 21:42:56
    Ever since Cicero’s De Natura Deorum ii.34., humans have been intrigued by the origin and mechanisms underlying complexity in nature. Darwin suggested that adaptation and complexity could evolve by natural selection acting successively on numerous small, heritable modifications. But is this enough? Here, we describe selected studies of experimental evolution with robots to illustrate how [...] (Source: Biosingularity)

  • Chemical Exposure Linked to Attention Deficit Disorder in Children

    Updated: 2010-01-30 16:49:13
    Children exposed in the womb to chemicals in cosmetics and fragrances are more likely to develop behavioral problems commonly found in children with attention deficit disorders, according to a study of New York City school-age children published Thursday. Scientists at Mount Sinai School of Medicine reported that mothers who had high levels of phthalates during their [...] (Source: Biosingularity)

  • Drug Discovery/Assay Development Scientist – BioPhase Solutions Inc – San Diego, CA

    Updated: 2010-01-30 01:09:39
    Scientist to work for a leading San Diego biotechnology company. Drug Discovery/Assay Development... pharmaceutical or biotechnology industry. Proficiency... From Monster - 30 Jan 2010 01:09:39 GMT - save job, email, more...

  • Mapping the brain

    Updated: 2010-01-29 04:04:40
    C. elegans, a tiny worm about a millimeter long, doesn’t have much of a brain, but it has a nervous system — one that comprises 302 nerve cells, or neurons, to be exact. In the 1970s, a team of researchers at Cambridge University decided to create a complete “wiring diagram” of how each of those [...] (Source: Biosingularity)

  • Surgical procedure urged for atrial fibrillation

    Updated: 2010-01-28 04:38:20
    People with atrial fibrillation, a common type of irregular heartbeat, should be referred for a surgical treatment called catheter ablation if an oral medication is not effective, said the authors of a study released Tuesday. In a head-to-head comparison of the two forms of treatment, catheter ablation was so superior in resolving the disorder and helping [...] (Source: Biosingularity)

  • Skin Cells Turned into Brain Cells

    Updated: 2010-01-28 04:36:45
    Skin cells called fibroblasts can be transformed into neurons quickly and efficiently with just a few genetic tweaks, according to new research. The surprisingly simple conversion, which doesn’t require the cells to be returned to an embryonic state, suggests that differentiated adult cells are much more flexible than previously thought. Cellular transformation: A cocktail of three [...] (Source: Biosingularity)

  • Magnesium May Improve Memory

    Updated: 2010-01-28 04:32:28
    New research finds that an increase in brain magnesium improves learning and memory in young and old rats. The study, published by Cell Press in the January 28th issue of the journal Neuron, suggests that increasing magnesium intake may be a valid strategy to enhance cognitive abilities and supports speculation that inadequate levels of magnesium impair [...] (Source: Biosingularity)

  • Scientists Discover a Controller of Brain Circuitry

    Updated: 2010-01-28 03:33:30
    By combining a research technique that dates back 136 years with modern molecular genetics, a Johns Hopkins neuroscientist has been able to see how a mammal’s brain shrewdly revisits and reuses the same molecular cues to control the complex design of its circuits. Details of the observation in lab mice, published Dec. 24 in Nature, reveal that [...] (Source: Biosingularity)

  • Human Growth Hormone: Not a Life Extender After All?

    Updated: 2010-01-28 03:26:12
    People profoundly deficient in human growth hormone (HGH) due to a genetic mutation appear to live just as long as people who make normal amounts of the hormone, a new study shows. The findings suggest that HGH may not be the “fountain of youth” that some researchers have suggested. “Without HGH, these people still live long, [...] (Source: Biosingularity)

  • New and improved RNA interference

    Updated: 2010-01-28 03:23:46
    Ever since RNA interference was discovered, in 1998, scientists have been pursuing the tantalizing ability to shut off any gene in the body — in particular, malfunctioning genes that cause diseases such as cancer. This week, researchers at MIT and Alnylam Pharmaceuticals report that they have successfully used RNA interference to turn off multiple genes in [...] (Source: Biosingularity)

  • Cellular memory hints at the origins of intelligence

    Updated: 2010-01-26 16:43:53
    Learning and memory — abilities associated with a brain or, at the very least, neuronal activity — have been observed in protoplasmic slime, a unicellular organism with multiple nuclei. When the amoeba Physarum polycephalum is subjected to a series of shocks at regular intervals, it learns the pattern and changes its behaviour in anticipation of the [...] (Source: Biosingularity)

  • Towards Creating Blood Vessels

    Updated: 2010-01-26 14:09:32
    An efficient new method of making endothelial cells, which give rise to blood vessels, could prove a huge boost for tissue engineering and regenerative medicine. By first finding a way to effectively tag endothelial cells, researchers at Weill Cornell Medical College developed a simple way to increase production of these cells by more than 30-fold. [...] (Source: Biosingularity)

  • More Sex Could Mean Less Heart Risk

    Updated: 2010-01-26 14:05:58
    Sex isn’t just good, it’s good for your heart, a new study of men indicates. Reporting in the American Journal of Cardiology, researchers say they’ve found that men with a low frequency of sexual activity have an increased risk of cardiovascular disease. Men who reported sexual activity of once a month or less had a higher risk [...] (Source: Biosingularity)

  • Treating depression by stimulating the pleasure center

    Updated: 2010-01-26 14:03:53
    Even with the best of available treatments, over a third of patients with depression may not achieve a satisfactory antidepressant response. Deep brain stimulation (DBS), a form of targeted electrical stimulation in the brain via implanted electrodes, is now undergoing careful testing to determine whether it could play a role in the treatment of patients [...] (Source: Biosingularity)

  • Low-Carb Diet Lowers Blood Pressure

    Updated: 2010-01-26 02:46:08
    A low-carbohydrate diet may have health benefits that go beyond weight loss. A new study shows that a low-carbohydrate diet was equally good as the weight loss drug orlistat (the active ingredient in Alli and Xenical) at helping overweight and obese people lose weight, but people who followed the low-carb diet also experienced a healthy drop [...] (Source: Biosingularity)

  • Cosmetics Testing without Animals

    Updated: 2010-01-24 17:41:30
    Researchers at Hurel Corporation have reached a major milestone in their quest to create a chip to replace skin allergy testing on animals. Working with cosmetics firm L’Oreal, Hurel has developed a working microfluidic portion of the chip. While there is still much work to be done before they have a whole chip ready for [...] (Source: Biosingularity)

  • First evidence that blueberry juice improves memory in older adults

    Updated: 2010-01-24 17:40:05
    Scientists are reporting the first evidence from human research that blueberries — one of the richest sources of healthful antioxidants and other so-called phytochemicals — improve memory. They said the study establishes a basis for comprehensive human clinical trials to determine whether blueberries really deserve their growing reputation as a memory enhancer. A report on the [...] (Source: Biosingularity)

  • Hungry immune guardians are snappier

    Updated: 2010-01-24 17:36:36
    Bonn researchers have discovered an elementary mechanism which regulates vital immune functions in healthy people. In situations of hunger which mean stress for the body’s cells, the body releases more antimicrobial peptides in order to protect itself. The scientists will publish their results in the journal Nature. T cells, B cells, antibodies are known as the ‘SWAT [...] (Source: Biosingularity)

  • Video of virus in action shows viruses can spread faster than thought possible

    Updated: 2010-01-24 17:32:48
    New video footage of a virus infecting cells is challenging what researchers have long believed about how viruses spread, suggesting that scientists may be able to create new drugs to tackle some viruses. Previously, viruses were thought to spread by entering a cell, replicating there, and then being released to infect new cells, so that the [...] (Source: Biosingularity)

  • Human running speeds of 35 to 40 mph may be biologically possible

    Updated: 2010-01-24 17:26:44
    amaican sprinter Usain Bolt’s record-setting performances have unleashed a wave of interest in the ultimate limits to human running speed. A new study published in the Journal of Applied Physiology offers intriguing insights into the biology and perhaps even the future of human running speed. The newly published evidence identifies the critical variable imposing the biological limit [...] (Source: Biosingularity)

  • Study identifies potential way to reverse cancer cell metabolism and tumor growth

    Updated: 2010-01-24 17:25:40
    A team of scientists led by Professor Adrian Krainer, Ph.D., of Cold Spring Harbor Laboratory has discovered molecular factors in cancer cells that boost the production of an enzyme that helps alter the cells’ glucose metabolism. The altered metabolic state, called the Warburg effect, promotes extremely rapid cell proliferation and tumor growth. Discovered eighty years ago [...] (Source: Biosingularity)

  • Extraordinary TEDMED Video About Growing New Organs

    Updated: 2010-01-24 00:31:01
    (Source: Biosingularity)

  • Made-to-Order Heart Cells

    Updated: 2010-01-24 00:22:06
    Last month, Madison, WI-based Cellular Dynamics International (CDI) began shipping heart cells derived from a person’s own stem cells. The cells could be useful to researchers studying everything from the toxicity of new or existing drugs to the electrodynamics of both healthy and diseased cardiac cells. CDI’s scientists create their heart cells–called iCell Cardiomyocytes–by taking cells [...] (Source: Biosingularity)

  • Cutting Salt as Good as Quitting Smoking

    Updated: 2010-01-24 00:20:41
    Cutting U.S. salt intake by just half a teaspoon a day would prevent up to 92,000 deaths, 99,000 heart attacks, and 66,000 strokes — a benefit as big as smoking cessation. That’s the prediction from computer models that used real clinical data to predict the effects of small reductions in salt intake. “The [ heart] benefits of [...] (Source: Biosingularity)

  • Vitamin D May Lower Colon Cancer Risk

    Updated: 2010-01-22 17:37:15
    Soaking in more sunlight and drinking more dairy may help you ward off colon cancer.Researchers in Europe have found that people with abundant levels of vitamin D — the so-called sunshine vitamin — have a much lower risk of colon cancer. The findings add to a growing body of evidence that suggest vitamin D may [...] (Source: Biosingularity)

  • Industrial Applications of Aspergillus

    Updated: 2010-01-20 23:18:00
    "This feast of hugely topical science culminates with an overview of novel industrial applications of Aspergillus oryzaee genomics (Abe et. al., Chapter 10), inciting much enthusiasm for potential applications or exploitations of similar methodologies in other Aspergillus species. Not only does this conclude the suite of species examined with our recognised industrial work horse for heterologous enzyme production, it also presents the opportunity to consider the application of Aspergillus species to biodegradation of plastics and how cell sensing and signalling mechanisms are integral to maximising success in all of the applications under consideration; cue a trans-genus comparison of signal reception and transduction and its relevance to drug screening."from Dr Elaine Bignell (Imperial Co...

  • Aspergillus book review

    Updated: 2010-01-20 23:15:00
    "...(a) feast of hugely topical science ... This book presents a modern-day dictionary of all things Aspergillus. It is highly readable and has been considerately crafted in terms of structure. From the very first chapter a sense of excitement about the new opportunities afforded by this fascinating genus is derived, which extends far beyond the interests of any single researcher but succeeds in capturing the relevance of genus-based findings for all who work with aspergilli. The essence of functional genomics and systems biology therefore permeates the volume, and ultimately the readers psyche. Not only does it provide a concise and highly current overview of Aspergillus genomics, it also manages to archive decades of relevant and highly insightful biology in a portable format. The book i...

  • Prolonged Sitting Boosts Bad Health

    Updated: 2010-01-20 04:54:22
    If you are reading this while sitting down, you might want to stand up for moment.A new editorial published in the British Journal of Sports Medicine suggests that people who sit still for prolonged periods of time — such as desk workers or coach potatoes — have a higher risk of disease than those who [...] (Source: Biosingularity)

  • Symbiotic Sloths

    Updated: 2010-01-18 02:44:55
    Viewed up close, the sloth appears as a hallucination, an ecosystem unto itself that softly vibrates with hundreds of exoparasites.spirulina The animal’s mottled appearance is due in part to a blue-green alga that lives symbiotically within its hollow hairs. Symbiotic Sloths Blogged with the Flock Browser

  • Lung Cancer Drug Zaps Tumor Blood Vessels

    Updated: 2010-01-17 04:12:42
    A new lung cancer drug that disrupts blood vessels within the tumor and inhibits blood flow to it looks promising, say researchers who are slated to report their findings Thursday at a cancer meeting in California. When added to traditional chemotherapy, the new drug, called vadimezan and also known as ASA404 or DMXAA, extended survival time, [...] (Source: Biosingularity)

  • Human immune cells — in mice

    Updated: 2010-01-17 04:08:24
    In 1796, English physician Edward Jenner decided to investigate a tale he had often heard — that milkmaids infected with cowpox became immune to smallpox, a much more dangerous affliction. To test this theory, Jenner inoculated an eight-year-old boy with pus from the blisters of a milkmaid who had caught cowpox. Two months later, Jenner [...] (Source: Biosingularity)

  • Fat in Rear Is Good for You

    Updated: 2010-01-15 19:38:36
    Pear trumps apple when it comes to body shape and your health.A new review suggests that having body fat stored in your thighs and backside may actually be good for you. Especially compared with the risks of storing excess fat around the mid-section.Researchers reviewed recent studies on the health effects of body fat distribution and [...] (Source: Biosingularity)

  • Non-Local Consciousness and the Revolution In Medicine : Part 1 : Healing Our Planet, Healing Our Selves

    Updated: 2010-01-15 16:33:48
    Healing Our Planet, Healing Ourselves is an ambitious collection of powerful ideas from some of the most advanced thinkers of our generation. In a series of interwoven essays and interviews, it explores the link between our individual wellness and the overall health of our ecosystems and planet, showing that they are inextricably linked. The thirty [...]

  • Sea slug surprise: It’s half-plant, half-animal – LiveScience- msnbc.com

    Updated: 2010-01-13 03:02:43
    Sea slug surprise: It’s half-plant, half-animal – LiveScience- msnbc.com

  • Nutrient mix shows promise in fighting Alzheimer’s

    Updated: 2010-01-13 02:42:16
    In the early stages of Alzheimer’s disease, patients typically suffer a major loss of the brain connections necessary for memory and information processing. Now, a combination of nutrients that was developed at MIT has shown the potential to improve memory in Alzheimer’s patients by stimulating growth of new brain connections. In a clinical trial of 225 [...] (Source: Biosingularity)

  • Needling Molecules

    Updated: 2010-01-13 02:40:17
    Many experiments in biology rely on manipulating cells: adding a gene, protein, or other molecule, for instance, to study its effects on the cell. But getting a molecule into a cell is much like breaking into a fortress; it often relies on biological tricks such as infecting a cell with a virus or attaching a [...] (Source: Biosingularity)

  • ‘Longevity’ Gene May Cut Dementia Risk

    Updated: 2010-01-13 02:34:37
    The so-called “longevity gene” may do more than add years to your life. It may also help stave off age-related cognitive decline, and this discovery is paving the way for new drugs to treat Alzheimer’s disease, a study shows. The longevity gene is a variant of the cholesteryl ester transfer protein (CETP) gene, which was discovered [...] (Source: Biosingularity)

  • Pomegranates May Stall Breast Cancer « Biosingularity

    Updated: 2010-01-06 21:23:33
    Eating pomegranates or drinking pomegranate juice may help prevent and slow the growth of some types of breast cancer.A new study shows a group of phytochemicals called ellagitannins found in abundance in pomegranates inhibited the growth of estrogen-responsive breast cancer in laboratory tests. Pomegranates May Stall Breast Cancer « Biosingularity

  • Pomegranates May Stall Breast Cancer

    Updated: 2010-01-05 15:13:54
    Eating pomegranates or drinking pomegranate juice may help prevent and slow the growth of some types of breast cancer. A new study shows a group of phytochemicals called ellagitannins found in abundance in pomegranates inhibited the growth of estrogen-responsive breast cancer in laboratory tests. via Pomegranates May Stall Breast Cancer. (Source: Biosingularity)

  • Are You Hungry?

    Updated: 2010-01-05 08:48:24
    Terry D. Etherton I have spent the last few weeks attending many Holiday celebrations and receptions.  A key component of these fabulous gatherings has been all of the delicious food.  In addition, I have received many food gifts from family, friends and colleagues. We are deeply fortunate to live in a country where there is “food galore”. [...]

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