• World Ecconomic Forum India Economic Summit | Collaborative strategy for drug discovery

    Updated: 2009-11-30 07:39:31
    The Coverage of the World Ecconomic Forum India Economic Summit is available at  http://blog.livemint.com/wefindia/ I was more interested in the Collaborative Strategy for Drug Development read the interview with Suven Lifesciences a prefered partner to Eli Lilly and Co in Drug Discoverya dn Development in India. http://www.livemint.com/2009/11/10204140/India-Economic-Summit–Collab.html  

  • Drug companies conducting their own clinical trials leads to Conflict of Interest a EU Debate

    Updated: 2009-11-30 00:05:14
    Ben Goldacre argues that the financial interests of drug companies lead to distorted evidence, but Vincent Lawton believes that adequate safeguards exist to keep bias in check. Full text of the article is published on BMJ Dr Goldacre and Prof Lawton faced each other on the same issue recently as opposing speakers at PharmaTimes’s Great Oxford Debate in [...]

  • ชีวเคมี 1

    Updated: 2009-11-26 05:54:18
    3102201    ชีวเคมี 1    Biochemistry I ธรรมชาติและชีวเคมีของสิ่งมีชีวิต โครงสร้างโมเลกุล คุณสมบัติทา

  • ชีวเคมี 2

    Updated: 2009-11-26 05:52:40
    3102202    ชีวเคมี 2    Biochemistry II เมตาบอลิสมของไนโตรเจนและกรดอะมิโน วงจรของยูเรีย สมบัติ และเม

  • ชีวเคมี 3

    Updated: 2009-11-26 05:48:57
    3102303    ชีวเคมี 3    Biochemistry III ความสัมพันธ์ของสารชีวโมเลกุลชนิดต่างๆ ในวิถีเมตาบอลิสมในอวั

  • ชีวเคมีขั้นสูงในสัตว์

    Updated: 2009-11-26 04:35:06
    3102741    ชีวเคมีขั้นสูงในสัตว์    Advanced Animal Biochemistry โครงสร้าง การสังเคราะห์ และหน้าที่ข

  • Study Sheds Light on Brain’s Fear Processing Center

    Updated: 2009-11-25 17:42:11
    Breathing carbon dioxide can trigger panic attacks, but the biological reason for this effect has not been understood. A new study by University of Iowa researchers shows that carbon dioxide increases brain acidity, which in turn activates a brain protein that plays an important role in fear and anxiety behavior. The study, published in the Nov. [...]

  • ชีวเคมี 1

    Updated: 2009-11-24 16:31:55
    3141103    ชีวเคมี 1    Biochemistry I โครงสร้างโมเลกุล หน้าที่ของน้ำ โปรตีน คาร์โบไฮเดรต ลิปิด กรดน

  • ชีวเคมี 2

    Updated: 2009-11-24 16:13:56
    3141206    ชีวเคมี 2    Biochemistry II พื้นฐานเมแทบอลิซึมของสารชีวโมเลกุล กระบวนการสังเคราะห์และการ

  • National Library of Medicine wants health care organizations to test drive Medical mapping tool

    Updated: 2009-11-24 09:23:29
    The National Library of Medicine wants health care organizations and vendors to test drive its new mapping tool that covers 5,000 standardized clinical terms , to create a standard medical vocabulary to support applications for electronic health records The Obama administration is distributing more than $19 billion in payments to doctors and hospitals that buy and [...]

  • Emerging Model Organisms for November

    Updated: 2009-11-23 22:07:24
    We’re getting toward the end of the second volume of our Emerging Model Organisms series in Cold Spring Harbor Protocols, and November’s issue brings us a look at the Hawaiian Bobtail Squid and the genus Dioscorea, or True Yams. Euprymna scolopes, the Hawaiian Bobtail Squid (our cover model this month, see below) is a cephalopod that’s [...]

  • ชีวเคมี

    Updated: 2009-11-23 08:25:23
    198145     ชีวเคมี     Biochemistry ชนิด โครงสร้าง คุณสมบัติ กระบวนการย่อย ดูดซึมและเผาผลาญของสารอาห

  • Myth=My sales people are wasting valuable time on Linkedin when they should be selling, Reality= Social Networking helps in Sales -Top execs say they are influenced by social networks

    Updated: 2009-11-20 11:22:36
    “My sales people are wasting valuable time on Facebook and Linkedin when they should be selling”: Now thats what most sales managers would say. I know thats true , I have irritated fare share of my managers by using social media to create and close sales and in lead generation. And I continue to do [...]

  • Glycolysis (and Gluconeogenesis)

    Updated: 2009-11-19 21:09:02
    Hey you masses of scientists!  Today, since I feel rather prepared for my biochemistry exam tomorrow

  • India looses USD 1 Billion Investment in Drug R&D to China due to lax Indian patent laws-

    Updated: 2009-11-19 08:37:17
    Did I really read the news correct or was I just plain drunk on a weekend while reading it. Turns out it is true. Just a week after the Novartis CEO has blasted the Indian IP laws, Novartis has announced plans to invest 1 Billion US Dollar in China for Drug Discovery and Developement. The [...]

  • Shorter Path to drug Discovery share research on failed compounds between companies the new MIT lead approach-

    Updated: 2009-11-18 08:52:44
    The moment I learned about this new project started by MIT, I could think of only one thing, I want to be part of it.  The Massachusetts Institute of Technology, have, started a pharmaceutical innovation program  to help drug companies adapt some successful approaches now used in aeronautics, like lean management and information-sharing among rivals. The [...]

  • Carver Charitable Trust Endows CCOM DNA Facility

    Updated: 2009-11-17 22:26:55
    Leaders of the Roy J. Carver Charitable Trust of Muscatine, Iowa, University of Iowa Health Care and the UI Foundation have announced a $2 million gift from the Carver Charitable Trust that will establish an operational endowment for the DNA Facility in the University of Iowa Roy J. and Lucille A. Carver College of Medicine. The [...]

  • BAP: Bimolecular Affinity Purification

    Updated: 2009-11-17 17:09:53
    The tandem affinity purification (TAP) procedure was pioneered in yeast for the purpose of purifying and characterizing protein complexes and has since been adapted for use in many organisms, including mammalian systems. The TAP procedure involves two sequential affinity purification steps to avoid non-specific protein interactions, a common problem in identifying proteins in complexes. [...]

  • Can we use the new Intel Product that Captures, Printed Text to Digital Text and then Reads Text- in clinical trials

    Updated: 2009-11-12 11:25:36
    Intel Corp.’s Digital Health Group has introduced a handheld product to convert printed text to digital text, then read it aloud to the user. The Intel Reader is designed for persons with dyslexia, other learning disabilities or impaired vision, according to the Santa Clara, Calif.-based vendor. The reader includes a high-resolution camera to point and shoot [...]

  • India begins serious efforts to ensure patient safety- Rejoice if you are in US Obama is going to penalize hospitals with high one-month readmission rates for transitioned patients

    Updated: 2009-11-12 10:07:33
    MUMBAI: A mop left inside a patient’s stomach after a surgery, an expired drug administered to an ailing person or a hospital-acquired infection-medical errors are a nightmare for both doctors and patients. Such incidents, which are usually swept under the carpet, will now be recorded and reported to an independent body in India. This will be [...]

  • UI Researchers Receive American Cancer Society Seed Grants

    Updated: 2009-11-10 18:22:31
    Three University of Iowa Carver College of Medicine researchers have each received a one-year, $30,000 American Cancer Society seed grant through Holden Comprehensive Cancer Center at the UI. The awards were effective Nov. 1. Songhai Chen, M.D., Ph.D., assistant professor of pharmacology, is investigating how to target certain proteins in order to inhibit the development and [...]

  • De Camilli to Speak as Part of Distinguished Scholar Series and Brody Lecture

    Updated: 2009-11-10 17:26:51
    A leading cellular neuroscientist will speak as part of the Carver College of Medicine’s Distinguished Biomedical Lecture Series.  Pietro, De Camilli, MD, Eugene Higgins Professor of Cell Biology and Neurobiology at Yale University will present “Molecular Mechanisms of Endocystosis” on Thursday, November 19 at 4 p.m.  De Camilli’s talk is also the Department of Pharmacology’s [...]

  • Horswill to Receive American Society for Microbiology Award

    Updated: 2009-11-10 17:19:48
    Alexander Horswill, PhD, assistant professor of microbiology has been selected by the American Society for Microbiology to receive a Merck Irving S. Sigal Memorial Award.  The award is one of only two such awards to be conferred by the society in 2010. The Merck Irving S. Sigal Memorial Award recognizes excellence in basic research in medical [...]

  • GST Fusion Proteins

    Updated: 2009-11-10 15:10:54
    Glutathione-S-transferase (GST) fusion proteins are used in a wide variety of applications in the lab. GST was originally selected as a fusion moiety because it’s not sequestered in inclusion bodies when expressed in bacteria and it can be affinity-purified without denaturation. Purification is fairly straightforward process, and GST fusion proteins are routinely used [...]

  • Warren Delano RIP

    Updated: 2009-11-07 16:29:59

  • Data Management and Integration for the Future of Clinical Trials webcast

    Updated: 2009-11-06 21:37:42
      Upcoming Webcast: Data Management and Integration for the Future of Clinical Trials Attend this interactive webcast presented by Applied Clinical Trials and Oracle Health Sciences featuring speaker Tom O’Leary, Senior Vice President, Data Management, ICON Clinical Research and Claire Castaings, Vice President Worldwide Director, Clinical Data Management Sanofi-Aventis. This session examines the use of the latest [...]

  • CSH Protocols accepted in PubMed

    Updated: 2009-11-06 18:13:21
    The National Library of Medicine (NLM) has informed us that Cold Spring Harbor Protocols has been selected to be indexed and included in MEDLINE, and that our articles will now be included and searchable using PubMed. We’re very pleased to share this announcement as it should make it easier for readers to find the [...]

  • FDA Webinar Drug Marketing and Advertising Are You Prepared for the Challenges of Social Media?

    Updated: 2009-11-06 13:31:32
    Since the FDA cracked down on social media marketing and online advertising, drugmakers have been walking on eggshells. A key FDA meeting is scheduled for Nov. 12-13. Read on … Drug [...]

  • Connect the physical world with digital information- Indian scientist work in MIT Media Lab

    Updated: 2009-11-05 10:51:42
    A PhD student at the Massachusetts Institute of Technology’s famed Media Lab, Mr Pranav Mistry, 28, has come a long way from being the president of the Young Scientists Club at hometown, Palanpur, in northern Gujarat, India ‘SixthSense’ is a wearable gestural interface that augments the physical world around us with digital information and lets us [...]

  • Campbell, Welsh Renewed as Howard Hughes Medical Institute Investigators

    Updated: 2009-11-04 17:51:28
    Two researchers in the University of Iowa Roy J. and Lucille A. Carver College of Medicine have been renewed for another five years as investigators of the Howard Hughes Medical Institute (HHMI). Both researchers, Kevin Campbell, Ph.D., and Michael Welsh, M.D., have been HHMI investigators since 1989. Based in Maryland, the institute was founded in 1953 [...]

  • How should you safely outsource pharmacovigilance to an Indian contract research organization?

    Updated: 2009-11-04 06:23:16
    Published in hte Indian Journal of Pharmacology. Edwards B. How should you safely outsource pharmacovigilance to an Indian contract research organization?. Indian J Pharmacol 2008;40:24-7   The articles focus on different types of CRO that operate in India and the concerns western companies should address before deciding to oursource the trial to Indian companies. exerpts from the article The [...]

  • High-Throughput Genotyping

    Updated: 2009-11-02 15:42:56
    The introduction of high-throughput laboratory methods has greatly increased the pace of research into the genetics of complex diseases. Instead of focusing only on one or a few coding variants in a small sample of individuals, the ability to accurately and efficiently genotype many individuals and to cover more of the variation within individual [...]

  • Scientists and social networks

    Updated: 2009-10-30 14:26:17
    I’ve recently written two pieces on scientists and social networks over at my other blogging gig, and thought they might be of interest to readers here: Scientists Still Not Joining Social Networks and NIH Funds a Social Network for Scientists–Is It Likely to Succeed?

  • Emerging Model Organisms for October

    Updated: 2009-10-28 19:20:33
    Volume 2 of our Emerging Model Organisms series rolls on in the October issue of Cold Spring Harbor Protocols. This month brings a look at two emerging models, one all-time classic. Neelima Sinha and colleagues present “The Mother of Thousands” (Kalanchoë daigremontiana), a plant which has the fascinating ability to regenerate and entire organism from [...]

  • First Chinese Clinical Research Outsourcing Industry Standard Under Development

    Updated: 2009-10-27 11:55:58
    According to information from the The Contract Research Organization Union China (CROU) under the China National Pharmaceutical Technology Market Association, it is developing the first industry standard for the Chinese CRO sector, Guidelines for Clinical Trial Services of Contract Research Organizations. Currently drafting of the document is already completed and it is likely to be [...]

  • Indian Council of Medical Research upgrade Clinical Trial Registry of India at par with international standards by WHO http://bit.ly/4fE5Yp

    Updated: 2009-10-27 09:22:10
    Indian Council of Medical Research (ICMR) has decided to upgrade the  Clinical Trial Registry of India (CTRI) on par with international standards as per the norms set by the WHO.

  • Indian Council of Medical Research upgrade Clinical Trial Registry of India at par with international standards by WHO http://bit.ly/4fE5Yp

    Updated: 2009-10-27 08:46:48
    Neil de Crescenzo, SVP Oracle Health Sciences http://tinyurl.com/yjklays Oracle in Health Sciences Industry http://tinyurl.com/yly257v

  • Oracle Health Sciences On YouTube, and Clinical Research Videos

    Updated: 2009-10-27 08:45:05
    Oracle Health Sciences Global Business Videos 1. Neil de Crescenzo, SVP and General Manager, Oracle Health Sciences http://tinyurl.com/yjklays 2. Oracle in Health Sciences Industry http://tinyurl.com/yly257v

  • Multi National Pharma sell their Captive Clinical Research Facilities in India

    Updated: 2009-10-23 11:53:47
    MNC pharma companies to control 8% of $20bn worth Indian medicines market by 2015. According to a FICCI study more than 60% of trials in India is conducted by Global Big Pharma companies.  Indian Clinical Research arena is often compared to the Indian outsourcing success and hte wave of BPO industry success in India. Multi national [...]

  • Coimmunoprecipitation in C. elegans

    Updated: 2009-10-22 15:10:11
    RNA molecules interact with proteins to drive many cellular activities, including post-transcriptional processing of RNA, regulation of translation, and transport of RNA to name but a few. These ribonucleoprotein complexes are isolated by coimmunoprecipitation (co-IP), where a protein-specific antibody is used to purify the protein of choice and its associated complex members. Analysis of [...]

  • twitter.com/clinicalsearch

    Updated: 2009-10-16 12:53:45
    Sinnce I am out of the pitch due to fever , I am going to be on my twitter for a while. May be head gone crazy or its the fever, But I was thinking why cant we use the tinyurl.com in Adverse event reporting, i mean the concept . I mean if [...]

  • Electronic Data Capture and Integration

    Updated: 2009-10-15 06:41:34
    In Conversation: Oracle’s Patti Gaves on EDC and Integration eCliniqua  in Conversation with industry veteran Patti Gaves of Oracle Health Sciences Global Business Unit, eCliniqua was curious about her perspective on the current status of electronic data capture (EDC), the industry’s strong focus on integration of electronic point solutions, and the evolution toward eClinical trials. Gaves, [...]

  • Optical Tweezers

    Updated: 2009-10-13 15:33:28
    Light carries momentum, so an object that reflects or refracts a beam of light experiences a force. This force is very small, but still strong enough to manipulate objects, such as a polystyrene bead. Using light focused through a lens, beads can be “trapped” near the focus. These optical traps, or “optical tweezers” [...]

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