Light carries momentum, so an object that reflects or refracts a beam of light experiences a force. This force is very small, but still strong enough to manipulate objects, such as a polystyrene bead. Using light focused through a lens, beads can be “trapped” near the focus. These optical traps, or “optical tweezers” [...]Congratulations go out to this year’s winners of the Nobel Prize for Medicine, Jack Szostak, Carol Greider and Elizabeth Blackburn for their pioneering work on telomeres. Cold Spring Harbor Laboratory Press is proud to be the publisher of Telomeres, a recent book on the subject co-edited by Blackburn.
Blackburn was interviewed by Joe [...]
This is a really well done animation describing the life cycle of HIV in great detail.
From YouThe study of RNA has long been the tool of choice for understanding where and when genes are expressed in a cell, tissue, or organism during development or under specific physiological or environmental conditions. Recent discoveries have revolutionized our concept of RNA function; it is now known to be active in a much wider [...]
The Carver College of Medicine DNA Facility has recently added 2 new instruments to support investigators in translational and personalized medicine studies. An Applied Biosystems SOLiD v3.1 Genome Sequencing System and a Fluidigm EP1 System for genetic analysis have both been recently installed and are available for use.
The Applied Biosystems SOLiD v3.1 Genome Sequencing System [...]
…or ‘what people have been looking for this week’.
“phosphate buffer in the 
Several Carver College of Medicine faculty members have been successful in receiving American Recovery and Reinvestment (ARRA) funds through National Institutes of Health awards. As of September 30, CCOM had received over 75 awards worth over $24.5 million in first-year funding. This includes 30 new competitive renewals and over 40 supplemental funding awards.
CCOM faculty responded in large numbers [...]
The University of Iowa Roy J. and Lucille A. Carver College of Medicine announces internal funding opportunities for Roy J. Carver Charitable Trust Medical Research Initiative Grants and Roy J. Carver Charitable Trust Collaborative Pilot Grants. Applications for each will be accepted through Tuesday, December 1, 2009 at 6:00 pm.
To be eligible for funding, principal [...]
The Carver College of Medicine Biomedical Research Store has recently launched a new website. The new site, at www.medicine.uiowa.edu/corefacilities/biostore/ allows investigators to view the Store’s inventory and after logging in, view product pricing.
Located on the second floor of Eckstein Medical Research Building, the Biomedical Research Store provides molecular and cell biology enzymes, reagents and kits [...]
Oxford Dictionary of Biochemistry and Molecular Biology
Download Full PDF Part1, PDF Part2
Francois Abboud, M.D., University of Iowa faculty member, has been appointed to the Decadal Survey on Biological and Physical Sciences in Space: Animal and Human Biology Panel, which operates through the National Academies.
The Space Studies Board and the Aeronautics and Space Engineering Board organized the group to establish priorities and provide recommendations for life and [...]
The University of Iowa Department of Microbiology together with the Carver College of Medicine will host E. Peter Greenberg, PhD on October 15 as part of the Distinguished Biomedical Scholars Lecture Series. Greenberg’s talk, “The Social Life of Bacteria,” will also be the first annual Michael A. Apicella Endowed Lecture in Microbiology. Distinguished Biomedical Scholars [...]
A 70 year-old English lady that lives alone is admitted to the hospital for evaluation of a leg w
A five-year, $5 million grant to establish a Center for the Prevention and Treatment of Visual Loss was awarded to the Iowa City Veterans Affairs (VA) Medical Center by the Veterans Affairs Division of Rehabilitation Research and Development.
The center will be led by Randy Kardon, M.D., Ph.D., UI professor of ophthalmology and visual sciences and [...]Phage-based E. coli homologous recombination systems have been extensively developed in recent years, and these recombination-mediated genetic engineering (”recombineering”) methods are now the preferred technique for carrying out genetic modifications in chromosomes and plasmids. Recombineering is efficient and precise and circumvents many of the problems of traditional genetic engineering methods, primarily the need to [...]Although many feel that RSS is dead, I still find it to be a highly useful tool for finding new interesting reading material. As such, we’re happy to announce some new functionality in Cold Spring Harbor Protocols involving our RSS feeds that send out alerts when new articles are published. Previously you could [...]Our long-running series of articles highlighting emerging model organisms continues in September with three entries, The Starlet Sea Anemone (Nematostella vectensis), Cephalochordates (Amphioxus or Lancelets) and The Western Clawed Frog (Xenopus tropicalis).
The slow rate of sequence evolution, the presumed high degree of preservation of ancestral traits, the ease of culturing, and the availability and experimental [...]Chromatin Immunoprecipitation (ChIP) is an invaluable method for studying the interactions between proteins and DNA on a genome-wide scale. ChIP can be used to determine whether a transcription factor interacts with a candidate target gene, and is used to monitor the presence of histones with posttranslational modifications at specific genomic locations. The results are often [...]